Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 1.00 |
| ▸ | SMARCA4 | P51532 | 8/20 | 1.00 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125262 | 1.00 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1MAPTGRM5 | |
| SCHEMBL22125459 | 0.86 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1MAPTGRM5 | |
| SCHEMBL25908086 | 0.85 | SMARCA2 (0.74) | SMARCA2SMARCA4MAPTMEN1KMT2A | |
| SCHEMBL22125249 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1MAPTGRM5 | |
| SCHEMBL30955596 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1MAPTGRM5 | |
| SCHEMBL22125446 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1HDAC4 | |
| SCHEMBL30955623 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1HDAC4 | |
| SCHEMBL9599834 | 0.78 | SMARCA2 (0.86) | SMARCA2SMARCA4MALT1MAPTS1PR2 | |
| SCHEMBL21722961 | 0.76 | SMARCA2 (0.61) | SMARCA2SMARCA4MEN1KMT2ARAB9A | |
| SCHEMBL22794203 | 0.74 | SMARCA2 (0.59) | SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666832-A | Urea compounds and compositions as SMARCA2/BRM atpase inhibitors | 诺华股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-112585136-B | Urea compounds and compositions as SMARCA2/BRM atpase inhibitors | 诺华股份有限公司 | 2024-06-25 | — | — | CN | disclosed |