Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 1.00 |
| ▸ | SMARCA4 | P51532 | 8/20 | 1.00 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125249 | 1.00 | SMARCA2 (1.00) | SMARCA2SMARCA4HTR2CHTR2AKMT2A | |
| SCHEMBL22125195 | 0.82 | SMARCA2 (1.00) | SMARCA2SMARCA4KMT2AMEN1PKM | |
| SCHEMBL9599834 | 0.81 | SMARCA2 (0.86) | SMARCA2SMARCA4KMT2ANPC1RAB9A | |
| SCHEMBL22125262 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4HTR2CHTR2AKMT2A | |
| SCHEMBL30955623 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1 | |
| SCHEMBL22125446 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4MALT1 | |
| SCHEMBL30955602 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4HTR2CHTR2AKMT2A | |
| SCHEMBL22125510 | 0.78 | SMARCA2 (0.81) | SMARCA2SMARCA4KMT2ANPC1RAB9A | |
| SCHEMBL11046021 | 0.77 | SMARCA2 (0.75) | SMARCA2SMARCA4KMT2ANPC1RAB9A | |
| SCHEMBL22125200 | 0.75 | SMARCA2 (1.00) | SMARCA2SMARCA4KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666832-A | Urea compounds and compositions as SMARCA2/BRM atpase inhibitors | 诺华股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-112585136-B | Urea compounds and compositions as SMARCA2/BRM atpase inhibitors | 诺华股份有限公司 | 2024-06-25 | — | — | CN | disclosed |