Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | TTK | P33981 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 6/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20654437 | 1.00 | MEN1 (0.41) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL15507750 | 0.88 | MEN1 (0.41) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL24339631 | 0.83 | MEN1 (0.40) | MEN1KMT2APIM1TTKPIM2 | |
| SCHEMBL29421498 | 0.83 | MEN1 (0.40) | MEN1KMT2APIM1TTKPIM2 | |
| SCHEMBL24340067 | 0.83 | MEN1 (0.42) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL15565833 | 0.83 | MEN1 (0.40) | MEN1KMT2APIM1TTKPIM2 | |
| SCHEMBL26341089 | 0.77 | MEN1 (0.40) | MEN1KMT2APIM1TTKPIM2 | |
| SCHEMBL26341112 | 0.77 | MEN1 (0.42) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL15206584 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL15598362 | 0.74 | MAPK1 (0.43) | MEN1KMT2ATTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131893-A1 | IRE1α SMALL MOLECULE INHIBITORS | SHANGHAI YI ZHONG XING BIOTECHNOLOGY CO., LTD. (CN) | 2024-06-27 | — | — | WO | disclosed |