Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 4/20 | 0.37 |
| ▸ | JAK1 | P23458 | 4/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30955736 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTGPR119HPGD | |
| SCHEMBL29107817 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTGPR119HPGD | |
| SCHEMBL16985361 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTGPR119HPGD | |
| SCHEMBL16794076 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTGPR119HPGD | |
| SCHEMBL16985425 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTGPR119HPGD | |
| SCHEMBL26341561 | 0.90 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTGPR119HPGD | |
| SCHEMBL16985405 | 0.89 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTGPR119HPGD | |
| SCHEMBL15192197 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTGPR119DDB1 | |
| SCHEMBL18383140 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTGPR119DDB1 | |
| SCHEMBL16794183 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTGPR119DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638454-A1 | SUBSTITUTED IMIDAZO-BASED COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK3 | Celgene Corporation (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137743-A1 | SUBSTITUTED IMIDAZO-BASED COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK3 | CELGENE CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |