SCHEMBL30956286

SCHEMBL30956286

Fc1ccc(Cc2nc3ccc(Cl)cc3[nH]2)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
F10 P00742 2/20 0.51
EGFR P00533 5/20 0.49
ERBB2 P04626 3/20 0.49
PCSK9 Q8NBP7 1/20 0.49
IDO1 P14902 1/20 0.49
RAB9A P51151 1/20 0.47
CACNA1B Q00975 1/20 0.46
PIK3CD O00329 2/20 0.46
PIK3CB P42338 2/20 0.46
PIK3CA P42336 1/20 0.46
BRS3 P32247 1/20 0.46
ALDH1A1 P00352 2/20 0.44
HTR3E A5X5Y0 1/20 0.44
HTR3B O95264 1/20 0.44
HTR3A P46098 1/20 0.44
BACE1 P56817 1/20 0.44
HTR3D Q70Z44 1/20 0.44
HTR3C Q8WXA8 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30956278 0.89 TDP1 (0.41) TDP1F10EGFRERBB2PCSK9
SCHEMBL30956285 0.85 F10 (0.48) TDP1F10PCSK9IDO1CACNA1B
SCHEMBL30956279 0.85 PCSK9 (0.43) F10EGFRPCSK9IDO1CACNA1B
SCHEMBL30956281 0.84 PDE10A (0.49) F10PCSK9IDO1CACNA1BPIK3CD
SCHEMBL29810805 0.79 EGFR (0.59) TDP1EGFRERBB2RAB9AALDH1A1
SCHEMBL2948135 0.79 EGFR (0.59) TDP1EGFRERBB2RAB9AALDH1A1
SCHEMBL30956287 0.79 TDP1 (0.46) TDP1F10EGFRERBB2IDO1
SCHEMBL30956289 0.78 PCSK9 (0.44) TDP1F10EGFRERBB2PCSK9
SCHEMBL30956280 0.78 PCSK9 (0.44) TDP1F10EGFRERBB2PCSK9
SCHEMBL30956288 0.76 PDE10A (0.52) TDP1F10EGFRERBB2PCSK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118007136-A Organic soldering-assisting protective agent containing fluorobenzimidazole derivative, and preparation method and application thereof 广东省科学院化工研究所 2024-05-10 CN disclosed