Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.69 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956739 | 1.00 | ADRB1 (0.69) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL20819580 | 1.00 | ADRB1 (0.69) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL20819581 | 1.00 | ADRB1 (0.69) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL20819687 | 0.86 | ADRB1 (0.58) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL30956714 | 0.86 | ADRB1 (0.58) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL9820962 | 0.86 | ADRB1 (0.58) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL30956709 | 0.86 | ADRB1 (0.58) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL20819577 | 0.83 | ADRB1 (0.55) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL20819576 | 0.83 | ADRB1 (0.55) | ADRB1ADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL30956724 | 0.83 | ADRB1 (0.55) | ADRB1ADRA2AADRA2BADRA2CADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930444-A | Fluorophenyl beta-hydroxyethylamine and its use in the treatment of hyperglycaemia | 阿托基公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-111148731-B | Fluorophenyl beta-hydroxyethylamine and its use in the treatment of hyperglycaemia | 阿托基公司 | 2024-07-09 | — | — | CN | disclosed |