SCHEMBL30957280

C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	15/20	0.46

▸	CALCR	P30988	15/20	0.46

▸	KEAP1	Q14145	3/20	0.44

▸	MC4R	P32245	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14028315	0.98	RAMP3 (0.46)	RAMP3CALCRKEAP1
SCHEMBL30868651	0.96	KEAP1 (0.44)	RAMP3CALCRKEAP1
SCHEMBL29905998	0.93	KEAP1 (0.45)	RAMP3CALCRKEAP1
SCHEMBL30868635	0.93	KEAP1 (0.45)	RAMP3CALCRKEAP1
SCHEMBL30868607	0.92	RAMP3 (0.46)	RAMP3CALCR
SCHEMBL30868640	0.92	NMUR2 (0.44)	RAMP3CALCRKEAP1
SCHEMBL30868648	0.90	IL23R (0.43)	RAMP3CALCR
SCHEMBL7935083	0.89	RAMP3 (0.46)	RAMP3CALCR
SCHEMBL10421719	0.89	RAMP3 (0.46)	RAMP3CALCR
Risuteganib SCHEMBL19410625	0.88	RAMP3 (0.42)	RAMP3CALCRKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4389216-A2	PEPTIDE COMPOSITIONS AND THERAPEUTIC USES	Allegro Pharmaceuticals, LLC (US)	2024-06-26	—	—	EP	disclosed