Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 5/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17490484 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2TP53SCN5ASCN9APDK1 | |
| SCHEMBL17490382 | 0.90 | RPS6KA5 (0.36) | SMN1; SMN2TP53SCN5ASCN9APDK1 | |
| SCHEMBL24900563 | 0.86 | EGFR (0.39) | TP53SCN5ASCN9APDK1CDK9 | |
| SCHEMBL30221535 | 0.86 | EGFR (0.39) | TP53SCN5ASCN9APDK1CDK9 | |
| SCHEMBL17490480 | 0.85 | PDK1 (0.50) | SMN1; SMN2PDK1GSK3BCDK5CDK9 | |
| SCHEMBL24900483 | 0.85 | PDK1 (0.42) | SMN1; SMN2SCN9APDK1GSK3BCDK5 | |
| SCHEMBL30957561 | 0.85 | PDK1 (0.42) | SMN1; SMN2SCN9APDK1GSK3BCDK5 | |
| SCHEMBL30957637 | 0.85 | PDK1 (0.50) | SMN1; SMN2PDK1GSK3BCDK5CDK9 | |
| SCHEMBL24900722 | 0.84 | PDK1 (0.39) | SMN1; SMN2TP53PDK1GSK3BCDK5 | |
| SCHEMBL30957512 | 0.84 | PDK1 (0.39) | SMN1; SMN2TP53PDK1GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |