Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24900377 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2POLBEGFR | |
| SCHEMBL17059345 | 0.81 | CCNB2 (0.51) | ALDH1A1POLBEGFRCCNB2CCNE2 | |
| SCHEMBL30166352 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2POLBEGFRPIK3CD | |
| SCHEMBL25238260 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2POLBEGFRPIK3CD | |
| SCHEMBL16340994 | 0.78 | FGFR2 (0.40) | ALDH1A1PIK3CDPIK3CAPIK3CGFGFR1 | |
| SCHEMBL30961488 | 0.78 | S1PR2 (0.39) | ALDH1A1KDM4ESMN1; SMN2POLBPIK3CD | |
| SCHEMBL25237512 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2POLBFGFR3 | |
| SCHEMBL30961370 | 0.73 | S1PR2 (0.42) | ALDH1A1SMN1; SMN2POLBCCNB2CCNE2 | |
| SCHEMBL24053363 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2POLBTTK | |
| SCHEMBL121368 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |