Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 8/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090361 | 1.00 | SSTR4 (0.40) | SSTR4SSTR1DRD4JAK2JAK1 | |
| SCHEMBL3981222 | 1.00 | SSTR4 (0.40) | SSTR4SSTR1DRD4JAK2JAK1 | |
| SCHEMBL3984347 | 0.84 | KCNH2 (0.39) | SSTR1SLC2A1KCNH2 | |
| SCHEMBL3107168 | 0.80 | PDE11A (0.31) | — | |
| SCHEMBL3100022 | 0.79 | PTPN11 (0.35) | SLC2A1KCNH2 | |
| SCHEMBL3982714 | 0.79 | PTPN11 (0.35) | SLC2A1KCNH2 | |
| SCHEMBL3102472 | 0.78 | CXCR4 (0.34) | SLC2A1KCNH2CHRM4 | |
| SCHEMBL3107031 | 0.78 | SPHK1 (0.37) | SLC2A1KCNH2 | |
| Hydrochloric Acid SCHEMBL3107676 | 0.77 | SLC2A1 (0.38) | SLC2A1KCNH2 | |
| SCHEMBL3100228 | 0.76 | CDK4 (0.31) | SLC2A1KCNH2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256124-A1 | Substituted 1-Methyl-1H-Quinolin-2-Ones And 1-Methyl-1H-1,5-Naphthyridin-2-Ones As Antibacterials | GLAXO GROUP LIMITED (GB) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256124-A1 | Substituted 1-Methyl-1H-Quinolin-2-Ones And 1-Methyl-1H-1,5-Naphthyridin-2-Ones As Antibacterials | TOP1, TOP2A, NDC1 | SSTR4 4842/4885SSTR1 4773/4885DRD4 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.