Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 5/20 | 0.61 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.60 |
| ▸ | INSR | P06213 | 5/20 | 0.60 |
| ▸ | IGF1R | P08069 | 3/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.56 |
| ▸ | ULK1 | O75385 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | NPM1 | P06748 | 1/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20516347 | 1.00 | TTK (0.61) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL30957983 | 0.89 | TTK (0.61) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL22256003 | 0.82 | ALK (0.54) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL29904712 | 0.81 | TTK (0.49) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL29561043 | 0.81 | EGFR (0.60) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL24091927 | 0.81 | ALK (0.57) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL21650062 | 0.81 | ALK (0.57) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL17197436 | 0.81 | TTK (0.52) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL22255956 | 0.80 | ALK (0.52) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL18912630 | 0.80 | INSR (0.68) | ALKINSRIGF1RLRRK2CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799190-B | Heterocyclic compounds | 卡都瑞恩医药有限公司 | 2024-04-19 | — | — | CN | disclosed |