Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.63 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.61 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.49 |
| ▸ | NPM1 | P06748 | 1/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21846967 | 0.79 | EGFR (1.00) | EGFRALKMETPTK2 | |
| SCHEMBL30957980 | 0.78 | EGFR (0.53) | EGFRALKIGF1RNPM1CAMK2D | |
| SCHEMBL15244057 | 0.78 | IGF1R (0.53) | EGFRALKMETIGF1RKCNH2 | |
| SCHEMBL15728552 | 0.78 | ALK (0.52) | EGFRALKMETIGF1RKCNH2 | |
| SCHEMBL18181661 | 0.77 | ALK (1.00) | EGFRALKMET | |
| SCHEMBL26611521 | 0.77 | EGFR (0.72) | EGFRALKMETIGF1RKCNH2 | |
| SCHEMBL3764899 | 0.76 | IGF1R (0.63) | EGFRALKMETIGF1RKCNH2 | |
| SCHEMBL2473309 | 0.76 | PDE4B (0.64) | — | |
| SCHEMBL520365 | 0.76 | ALK (0.80) | ALKKCNH2PTK2NPM1 | |
| SCHEMBL15725873 | 0.75 | EGFR (0.49) | EGFRALKMETIGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799190-B | Heterocyclic compounds | 卡都瑞恩医药有限公司 | 2024-04-19 | — | — | CN | disclosed |