SCHEMBL30958077

CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)O)N(C)C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.62

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	APLNR	P35414	2/20	0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30958093	0.93	APLNR (0.59)	APLNR
SCHEMBL30958095	0.88	APLNR (0.81)	APLNR
SCHEMBL30958096	0.83	APLNR (0.86)	APLNR
SCHEMBL30537453	0.83	CXCR4 (0.57)	APLNR
SCHEMBL31529690	0.83	APLNR (0.60)	APLNR
SCHEMBL29569355	0.83	C5AR1 (0.55)	APLNR
SCHEMBL29607540	0.83	C5AR1 (0.56)	APLNR
SCHEMBL30958099	0.82	APLNR (0.47)	APLNR
SCHEMBL29608128	0.82	CXCR4 (0.57)	APLNR
SCHEMBL30537456	0.82	APLNR (0.55)	APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3649146-B1	APELIN PEPTIDES AND USES THEREOF	UNIV ALBERTA (CA)	2024-06-26	—	—	EP	disclosed