Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425087 | 0.90 | KDM4E (0.59) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL7427655 | 0.88 | KDM4E (0.35) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL9269234 | 0.86 | KDM4E (0.50) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL14957475 | 0.82 | ALOX15 (0.43) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL21121534 | 0.81 | NOTUM (0.33) | ALOX15TSHR | |
| SCHEMBL431671 | 0.77 | KDM4E (0.41) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL28778217 | 0.76 | KDM4E (0.43) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL9797391 | 0.74 | KDM4E (0.48) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL8037231 | 0.73 | KDM4E (0.86) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL14424336 | 0.73 | SMN1; SMN2 (0.39) | KDM4EMAPTMEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271201-A | With NMDA receptor-Ca2+Heterodiad compound with channel as target point, and preparation method and application thereof | 合肥工业大学 | 2024-07-02 | — | — | CN | disclosed |