Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.68 |
| ▸ | GPR84 | Q9NQS5 | 12/20 | 0.60 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | PPARD | Q03181 | 7/20 | 0.60 |
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TLR2 | O60603 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL30817662 | 1.00 | FFAR4 (0.68) | FFAR4FFAR1GPR84PPARGPPARD | |
| Succinic Acid SCHEMBL30084362 | 1.00 | FFAR4 (0.68) | FFAR4FFAR1GPR84PPARGPPARD | |
| Succinic Acid SCHEMBL29780365 | 0.98 | FFAR4 (0.64) | FFAR4FFAR1GPR84PPARGPPARD | |
| Succinic Acid SCHEMBL4667883 | 0.98 | FFAR4 (0.64) | FFAR4FFAR1GPR84PPARGPPARD | |
| Arachidic Acid SCHEMBL17812737 | 0.94 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| Palmitic Acid SCHEMBL17812630 | 0.94 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| Tridecanoate SCHEMBL17812452 | 0.94 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| Dodecanoate SCHEMBL17812524 | 0.94 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| Azelaic Acid SCHEMBL8575519 | 0.94 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD | |
| Sebacic Acid SCHEMBL8574592 | 0.94 | FFAR4 (0.78) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271530-A | Preparation method and application of hybrid resin | 南京聚发新材料有限公司 | 2024-07-02 | — | — | CN | disclosed |