Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL29780365 | 1.00 | FFAR4 (0.64) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Succinic Acid SCHEMBL30084362 | 0.98 | FFAR4 (0.68) | FFAR4FFAR1GPR84PPARGPPARD | |
| Succinic Acid SCHEMBL30817662 | 0.98 | FFAR4 (0.68) | FFAR4FFAR1GPR84PPARGPPARD | |
| Succinic Acid SCHEMBL30958737 | 0.98 | FFAR4 (0.68) | FFAR4FFAR1GPR84PPARGPPARD | |
| Adipic Acid SCHEMBL630307 | 0.93 | FFAR4 (0.74) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Butyric Acid SCHEMBL27673321 | 0.93 | FFAR4 (0.62) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Glutarate SCHEMBL28543960 | 0.93 | FFAR4 (0.68) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Succinic Acid SCHEMBL28075979 | 0.93 | FFAR4 (0.55) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Palmitic Acid SCHEMBL17812630 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Arachidic Acid SCHEMBL17812737 | 0.91 | FFAR4 (0.78) | FFAR4FFAR1AKR1B1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241997-A | Plastic compound additive and preparation method thereof | 徐州华云精细化工有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-118703150-A | High-performance polyester hot melt adhesive and preparation method thereof | 佛山格邦高分子科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-109705794-B | Low-viscosity UV/moisture dual-curing polyurethane hot melt adhesive and preparation method thereof | 重庆中科力泰高分子材料股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-113462346-B | UV/moisture dual-curing polyurethane hot melt adhesive with high initial adhesion and excellent drop resistance, and preparation method and application thereof | 重庆中科力泰高分子材料股份有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-107406568-B | Crystalline thermoplastic polyurethane composition for hot melt adhesives | 路博润先进材料公司 | 2021-02-19 | — | — | CN | claimed |
| CN-107121902-B | Toner compositions and methods | 施乐公司 | 2020-11-27 | — | — | CN | claimed |
| EP-3268407-B1 | CRYSTALLINE THERMOPLASTIC POLYURETHANE COMPOSITION FOR HOT-MELT ADHESIVES | LUBRIZOL ADVANCED MAT INC (US) | 2019-01-09 | — | — | EP | claimed |
| US-20180051120-A1 | Crystalline Thermoplastic Polyurethane Composition for Hot-Melt Adhesives | LUBRIZOL ADVANCED MATERIALS, INC. | 2018-02-22 | — | — | US | claimed |
| EP-3268407-A1 | CRYSTALLINE THERMOPLASTIC POLYURETHANE COMPOSITION FOR HOT-MELT ADHESIVES | Lubrizol Advanced Materials, Inc. (US) | 2018-01-17 | — | — | EP | claimed |
| WO-2016144676-A1 | CRYSTALLINE THERMOPLASTIC POLYURETHANE COMPOSITION FOR HOT-MELT ADHESIVES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2016-09-15 | — | — | WO | claimed |
| CN-119241997-A | Plastic compound additive and preparation method thereof | 徐州华云精细化工有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-118703150-A | High-performance polyester hot melt adhesive and preparation method thereof | 佛山格邦高分子科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118271530-A | Preparation method and application of hybrid resin | 南京聚发新材料有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114366808-B | Polysaccharide and virus antigen co-delivery nano vaccine, and preparation method and application thereof | 南京农业大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-116804836-A | Toner containing charge control agent | 施乐公司 | 2023-09-26 | — | — | CN | disclosed |
| US-20050249954-A1 | Method of Forming Multilayer Coating Films and Multilayer Coating Films | NIPPON PAINT CO., LTD. (JP) | 2005-11-10 | — | — | US | disclosed |
| US-6649700-B2 | Storage stability, appearance of film formed, for coating automobile bodies | NIPPON PAINT CO., LTD. (JP) | 2003-11-18 | — | — | US | disclosed |
| US-20020086104-A1 | Thermosetting powder coating composition and curing agent composition | YABUTA MASAMI (JP) | 2002-07-04 | — | — | US | disclosed |
| US-6313221-B1 | STORAGE STABILITY; CAPABLE OF PROVIDING COATING FILMS SMOOTHNESS AND APPEARANCE | NIPPON PAINT CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1055694-A2 | Thermosetting powder coating composition and curing agent composition | Nippon Paint Co., Ltd. (JP) | 2000-11-29 | — | — | EP | disclosed |