Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | CASP7 | P55210 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30959122 | 0.86 | HPGD (0.36) | HPGDALDH1A1HSD17B10KDM4ECASP1 | |
| SCHEMBL30959145 | 0.82 | RXRA (0.36) | ALDH1A1RXRARXRBRXRGCYP4F2 | |
| SCHEMBL21243954 | 0.80 | RXRA (0.41) | ALDH1A1RXRARXRBRXRGMAPT | |
| SCHEMBL30959270 | 0.80 | RXRA (0.38) | ALDH1A1RXRARXRBRXRGCYP4F2 | |
| SCHEMBL30959494 | 0.79 | RXRA (0.37) | ALDH1A1RXRARXRBRXRGCYP4F2 | |
| SCHEMBL31725782 | 0.79 | RXRA (0.36) | ALDH1A1RXRARXRBRXRGCYP4F2 | |
| SCHEMBL30959428 | 0.78 | RXRA (0.37) | ALDH1A1RXRARXRBRXRGCYP4F2 | |
| SCHEMBL30959571 | 0.77 | RXRA (0.36) | ALDH1A1RXRARXRBRXRGCYP4F2 | |
| SCHEMBL30959568 | 0.77 | RXRA (0.36) | ALDH1A1RXRARXRBRXRGCYP4F2 | |
| SCHEMBL30952509 | 0.77 | CYP4F2 (0.41) | ALDH1A1RXRARXRBRXRGCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615847-A1 | SMALL MOLECULE INHIBITORS OF KRAS PROTEINS | Merck Sharp & Dohme LLC (US) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024103010-A1 | SMALL MOLECULE INHIBITORS OF KRAS PROTEINS | MERCK SHARP & DOHME LLC (US) | 2024-05-16 | — | — | WO | disclosed |