Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.74 |
| ▸ | MEN1 | O00255 | 11/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.74 |
| ▸ | HPGD | P15428 | 10/20 | 0.74 |
| ▸ | LMNA | P02545 | 10/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | GAA | P10253 | 7/20 | 0.74 |
| ▸ | RAB9A | P51151 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | NPC1 | O15118 | 5/20 | 0.74 |
| ▸ | PRNP | P04156 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22994346 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL22994347 | 0.92 | MEN1 (0.70) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL30960490 | 0.92 | MEN1 (0.70) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL22994351 | 0.91 | MEN1 (0.60) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL30960487 | 0.91 | MEN1 (0.60) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL22978670 | 0.88 | MEN1 (0.74) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL30960491 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL22994342 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL15617147 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL15617134 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015510-B1 | ANTI-TUMOUR COMPOUND BASED ON JWA GENE ACTIVATION AND HER2 DEGRADATION, PREPARATION METHOD THEREFOR, AND USE THEREOF | Simcere pharmaceutical co ltd (CN) | 2025-08-20 | — | — | EP | claimed |
| CN-113402479-B | Antitumor compound based on JWA gene activation and HER2 degradation, preparation method and application thereof | 先声药业有限公司 | 2024-05-17 | — | — | CN | claimed |