Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | HPGD | P15428 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 10/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 11/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22994348 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL30960488 | 0.88 | MEN1 (0.62) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL22994352 | 0.88 | MEN1 (0.62) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL30960491 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL22994342 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL22994344 | 0.83 | MEN1 (0.52) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL30960485 | 0.83 | MEN1 (0.52) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL2138195 | 0.73 | MAPT (0.61) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL22978670 | 0.72 | MEN1 (0.74) | ALDH1A1HPGDMAPTLMNARAB9A | |
| SCHEMBL22994346 | 0.72 | ALDH1A1 (0.74) | ALDH1A1HPGDMAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015510-B1 | ANTI-TUMOUR COMPOUND BASED ON JWA GENE ACTIVATION AND HER2 DEGRADATION, PREPARATION METHOD THEREFOR, AND USE THEREOF | Simcere pharmaceutical co ltd (CN) | 2025-08-20 | — | — | EP | claimed |
| CN-113402479-B | Antitumor compound based on JWA gene activation and HER2 degradation, preparation method and application thereof | 先声药业有限公司 | 2024-05-17 | — | — | CN | claimed |