Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SIK1 | P57059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962866 | 1.00 | IGF1R (0.44) | IGF1RMAPTJAK3PTK2SRC | |
| SCHEMBL30962735 | 1.00 | IGF1R (0.44) | IGF1RMAPTJAK3PTK2SRC | |
| SCHEMBL30962691 | 0.97 | IGF1R (0.42) | IGF1RMAPTJAK3PTK2SRC | |
| SCHEMBL30962722 | 0.97 | IGF1R (0.42) | IGF1RMAPTJAK3PTK2SRC | |
| SCHEMBL30962726 | 0.97 | IGF1R (0.42) | IGF1RMAPTJAK3PTK2SRC | |
| SCHEMBL30962749 | 0.89 | PIK3CD (0.43) | IGF1RSRCCCNKCCNA2CDK2 | |
| SCHEMBL30962935 | 0.88 | WEE1 (0.46) | JAK3PTK2SRCSIK1SIK2 | |
| SCHEMBL30962635 | 0.88 | WEE1 (0.46) | JAK3PTK2SRCSIK1SIK2 | |
| SCHEMBL30962914 | 0.88 | WEE1 (0.46) | JAK3PTK2SRCSIK1SIK2 | |
| SCHEMBL30962752 | 0.88 | MAPT (0.43) | IGF1RMAPTJAK3PTK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |