Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | CCND3 | P30281 | 2/20 | 0.39 |
| ▸ | CCNK | O75909 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | SIK1 | P57059 | 2/20 | 0.39 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.39 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962722 | 1.00 | IGF1R (0.42) | IGF1RSRCCCND3CCNKCCNA2 | |
| SCHEMBL30962726 | 1.00 | IGF1R (0.42) | IGF1RSRCCCND3CCNKCCNA2 | |
| SCHEMBL30962660 | 0.97 | IGF1R (0.44) | IGF1RSRCCCND3CCNKCCNA2 | |
| SCHEMBL30962735 | 0.97 | IGF1R (0.44) | IGF1RSRCCCND3CCNKCCNA2 | |
| SCHEMBL30962866 | 0.97 | IGF1R (0.44) | IGF1RSRCCCND3CCNKCCNA2 | |
| SCHEMBL30962711 | 0.89 | SRC (0.43) | SRCSIK1SIK2SIK3JAK3 | |
| SCHEMBL30962729 | 0.89 | SRC (0.43) | SRCSIK1SIK2SIK3JAK3 | |
| SCHEMBL30962855 | 0.89 | SRC (0.43) | SRCSIK1SIK2SIK3JAK3 | |
| SCHEMBL30962615 | 0.87 | WEE1 (0.48) | SRCSIK1SIK2SIK3JAK3 | |
| SCHEMBL30962635 | 0.86 | WEE1 (0.46) | SRCSIK1SIK2SIK3JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |