Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 6/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | SIK1 | P57059 | 2/20 | 0.39 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.39 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962685 | 0.97 | SRC (0.38) | TTKSRCLCKJAK3KDR | |
| SCHEMBL30962908 | 0.91 | WEE1 (0.43) | SRCLCKJAK3KDRTEK | |
| SCHEMBL30962681 | 0.89 | TTK (0.43) | TTKSRCLCKJAK3KDR | |
| SCHEMBL30962922 | 0.86 | WEE1 (0.44) | SRCLCKJAK3KDRTEK | |
| SCHEMBL30962719 | 0.86 | PTK2 (0.40) | SRCLCKJAK3KDRTEK | |
| SCHEMBL30962930 | 0.86 | SRC (0.46) | TTKSRCLCKJAK3KDR | |
| SCHEMBL30962929 | 0.86 | SRC (0.46) | TTKSRCLCKJAK3KDR | |
| SCHEMBL30962942 | 0.86 | SRC (0.41) | TTKSRCLCKJAK3KDR | |
| SCHEMBL30962674 | 0.86 | SRC (0.41) | TTKSRCLCKJAK3KDR | |
| SCHEMBL30962817 | 0.84 | LCK (0.43) | TTKSRCLCKJAK3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |