Methenamine

Methenamine

SCHEMBL3096283

C1N2CN3CN1CN(C2)C3.Nc1ccc(N)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.57
ALDH1A1 P00352 9/20 0.47
CYP3A4 P08684 6/20 0.47
TDP1 Q9NUW8 6/20 0.47
TP53 P04637 2/20 0.47
ALOX15 P16050 3/20 0.42
MAPK1 P28482 3/20 0.42
HSD17B10 Q99714 3/20 0.42
THRB P10828 2/20 0.42
ACHE P22303 1/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CASP1 P29466 1/20 0.42
HIF1A Q16665 1/20 0.42
CA14 Q9ULX7 1/20 0.42
TSHR P16473 4/20 0.40
GFER P55789 3/20 0.40
NPC1 O15118 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methenamine SCHEMBL20637784 0.78 TDP1 (0.70) MAPTALDH1A1CYP3A4TDP1TP53
SCHEMBL320609 0.76 MEN1 (1.00) MAPTKMT2AMEN1ALDH1A1CYP3A4
SCHEMBL27981 0.76
Ammonia Solution, Strong SCHEMBL1658729 0.71 MEN1 (0.89) MAPTKMT2AMEN1ALDH1A1CYP3A4
Fluoride SCHEMBL20497199 0.71 MEN1 (0.89) MAPTKMT2AMEN1ALDH1A1CYP3A4
Fluoride SCHEMBL10704561 0.71 MEN1 (0.89) MAPTKMT2AMEN1ALDH1A1CYP3A4
SCHEMBL6537437 0.71
Hydrochloric Acid SCHEMBL378591 0.71 MEN1 (0.89) MAPTKMT2AMEN1ALDH1A1CYP3A4
SCHEMBL1652426 0.71
SCHEMBL21749649 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325155-B1 STABILIZED COMPOSITIONS COMPRISING AMMONIUM NITRATE ADVANSIX RESINS & CHEMICALS LLC (US) 2019-05-08 EP claimed
US-8814977-B2 Stabilized compositions comprising ammonium nitrate HONEYWELL INTERNATIONAL INC. (US) 2014-08-26 US claimed
US-20120180538-A1 STABILIZED COMPOSITIONS COMPRISING AMMONIUM NITRATE HONEYWELL INTERNATIONAL INC. (US) 2012-07-19 US claimed
US-20100254880-A1 STABILIZED COMPOSITIONS COMPRIZING AMMONIUM NITRATE HONEYWELL INTERNATIONAL INC. (US) 2010-10-07 US claimed