Methenamine

Methenamine

SCHEMBL20637784

C1N2CN3CN1CN(C2)C3.COc1ccc(N)cc1.[Ru]

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.70
MAPK1 P28482 1/20 0.70
ALDH1A1 P00352 3/20 0.67
CYP3A4 P08684 2/20 0.67
APP P05067 2/20 0.55
NR4A1 P22736 1/20 0.55
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
MAPT P10636 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
NFKB1 P19838 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5097 0.83
SCHEMBL8526630 0.83 TDP1 (1.00) TDP1MAPK1ALDH1A1CYP3A4APP
Cyclopropane SCHEMBL7209694 0.81 TDP1 (0.84) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL7214917 0.81 TDP1 (0.84) TDP1MAPK1ALDH1A1CYP3A4APP
Hydrochloric Acid SCHEMBL3947579 0.81 ALDH1A1 (1.00) TDP1MAPK1ALDH1A1CYP3A4APP
Methane SCHEMBL22289589 0.81 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL357435 0.81 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL21840887 0.81 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL5601373 0.81 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4APP
Hydrochloric Acid SCHEMBL208637 0.81 ALDH1A1 (1.00) TDP1MAPK1ALDH1A1CYP3A4APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10620146-B2 Electrode chip TOHOKU UNIVERSITY (JP) 2020-04-14 US disclosed
US-20190017953-A1 ELECTRODE TIP TOHOKU UNIVERSITY (JP) 2019-01-17 US disclosed