Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.53 |
| ▸ | KCNQ5 | Q9NR82 | 4/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | JUN | P05412 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437928 | 0.78 | KMT2A (0.80) | TYK2MEN1LMNAKMT2A | |
| SCHEMBL2946609 | 0.78 | NFKB1 (0.52) | TYK2MEN1LMNAKMT2AJUN | |
| SCHEMBL9845318 | 0.74 | LCK (0.57) | KMT2AHDAC1HDAC6NPSR1 | |
| SCHEMBL683823 | 0.74 | MEN1 (0.68) | TYK2MEN1LMNAKMT2AJAK2 | |
| SCHEMBL14652150 | 0.72 | LCK (0.55) | HDAC1HDAC6 | |
| SCHEMBL30962730 | 0.72 | POLB (0.46) | TYK2MEN1KMT2ANFKB1 | |
| SCHEMBL4730214 | 0.72 | HDAC1 (1.00) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL28488060 | 0.72 | NPC1 (0.56) | MEN1LMNAKMT2AHDAC3HDAC1 | |
| SCHEMBL9845369 | 0.71 | LCK (0.54) | NFKB1NFKB2RELA | |
| SCHEMBL16210003 | 0.71 | P4HTM (0.51) | TYK2MEN1LMNAKMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |