Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 14/20 | 0.56 |
| ▸ | JUN | P05412 | 8/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 8/20 | 0.56 |
| ▸ | RELA | Q04206 | 8/20 | 0.56 |
| ▸ | XPO1 | O14980 | 5/20 | 0.52 |
| ▸ | ATF1 | P18846 | 7/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962949 | 1.00 | NFKB1 (0.56) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL31236240 | 0.89 | NFKB1 (0.56) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL30962910 | 0.83 | NFKB1 (0.47) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL2946609 | 0.82 | NFKB1 (0.52) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL30962889 | 0.80 | NFKB1 (0.50) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL16453386 | 0.80 | NFKB1 (0.50) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL28557381 | 0.78 | NFKB1 (0.61) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL30421262 | 0.78 | NFKB1 (0.61) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL30962892 | 0.75 | NFKB1 (0.57) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL2949398 | 0.74 | RXFP1 (0.51) | NFKB1JUNNFKB2RELAXPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |