Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | PDE1A | P54750 | 2/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035909 | 0.80 | CDK9 (0.46) | BRD4BAZ2ACDK9CYP11B2 | |
| SCHEMBL25164914 | 0.77 | BRD4 (0.37) | BRD4BAZ2AGRIN2BCYP1A2CYP2C9 | |
| SCHEMBL31637178 | 0.75 | BRD4 (0.42) | BRD4BAZ2AKCNH2PIK3CDPI4KA | |
| SCHEMBL23442015 | 0.73 | KDM4E (0.42) | — | |
| SCHEMBL16520001 | 0.72 | HRH3 (0.45) | BRD4BAZ2AKCNH2PIK3CDPI4KA | |
| SCHEMBL25204462 | 0.72 | PDE8B (0.41) | BRD4BAZ2AMTOR | |
| SCHEMBL30962978 | 0.72 | PDE2A (0.34) | BRD4BAZ2AKCNH2PDE1CPDE1A | |
| SCHEMBL16036777 | 0.71 | GRIN2B (0.52) | BRD4KCNH2GRIN2BCYP1A2CYP2C9 | |
| SCHEMBL30962975 | 0.71 | CHEK2 (0.52) | BRD4CHEK1CHEK2 | |
| SCHEMBL25243664 | 0.70 | PDE8B (0.39) | BRD4BAZ2AGRIN2BCDK9MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646414-A1 | CDK2 INHIBITORS | Blueprint Medicines Corporation (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024148091-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2024-07-11 | — | — | WO | disclosed |