Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.56 |
| ▸ | JAK1 | P23458 | 7/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963331 | 0.88 | TYK2 (0.68) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL30636228 | 0.87 | TYK2 (0.61) | TYK2JAK1KCNH2 | |
| SCHEMBL30385114 | 0.86 | TYK2 (0.58) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL30963334 | 0.84 | TYK2 (0.58) | TYK2JAK1STAT3JAK2STAT1 | |
| SCHEMBL30385234 | 0.84 | TYK2 (0.62) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL30385236 | 0.80 | TYK2 (0.63) | TYK2JAK1KCNH2STAT3JAK2 | |
| SCHEMBL30963332 | 0.79 | TYK2 (0.59) | TYK2JAK1STAT3JAK2STAT1 | |
| SCHEMBL29362041 | 0.78 | TYK2 (0.80) | TYK2JAK1STAT3JAK2STAT1 | |
| SCHEMBL30466384 | 0.77 | TYK2 (0.67) | TYK2JAK1STAT3 | |
| SCHEMBL29684670 | 0.76 | TYK2 (0.43) | TYK2JAK1KCNH2JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125651-A1 | NOVEL ACRYLIC ACID DERIVATIVE WITH HETEROCYCLE SUBSTITUTION AND USE THEREOF | 津药生物科技（天津）有限公司 | 2024-06-20 | — | — | WO | disclosed |