Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.61 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466384 | 0.89 | TYK2 (0.67) | TYK2JAK1CYP2C19 | |
| SCHEMBL30963333 | 0.87 | TYK2 (0.56) | TYK2JAK1KCNH2 | |
| SCHEMBL30385380 | 0.85 | TYK2 (0.45) | TYK2JAK1CYP2C19NUDT1 | |
| SCHEMBL30636414 | 0.85 | TYK2 (0.61) | TYK2JAK1CYP2C19 | |
| SCHEMBL31218707 | 0.82 | TYK2 (0.57) | TYK2JAK1CYP2C19NUDT1KCNH2 | |
| SCHEMBL30636204 | 0.82 | TYK2 (0.57) | TYK2JAK1CYP2C19NUDT1KCNH2 | |
| SCHEMBL28975902 | 0.80 | TYK2 (0.72) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30227455 | 0.80 | TYK2 (0.72) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30490067 | 0.80 | TYK2 (0.44) | TYK2JAK1CYP2C19NUDT1 | |
| SCHEMBL30490075 | 0.79 | TYK2 (0.51) | TYK2JAK1CYP2C19NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213308-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2023-11-09 | — | — | WO | claimed |
| WO-2023213308-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2023-11-09 | — | — | WO | disclosed |