Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.70 |
| ▸ | MMP12 | P39900 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 7/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957529 | 1.00 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL3080762 | 0.90 | PRKCA (0.71) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL3079634 | 0.90 | PRKCA (0.71) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL395908 | 0.89 | PRKCA (0.59) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL4211798 | 0.89 | PRKCA (0.57) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL3098287 | 0.87 | PRKCA (0.81) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL14110618 | 0.87 | PRKCA (0.71) | PRKCAMMP12NR1I2SCN9AKMO | |
| SCHEMBL2957655 | 0.86 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL3088711 | 0.86 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL771226 | 0.86 | PRKCA (0.66) | PRKCAMMP12NR1I2SCN9AKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795247-B2 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | claimed |