Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | DHPS | P49366 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | JAK1 | P23458 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853888 | 1.00 | NPC1 (0.62) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL15546532 | 0.85 | NPC1 (0.63) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL11735958 | 0.84 | ALDH1A1 (0.61) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL21894632 | 0.84 | GAA (0.64) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL17739081 | 0.83 | NPC1 (0.78) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL20442319 | 0.82 | TRPV1 (0.62) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL20442321 | 0.82 | TRPV1 (0.70) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL11949095 | 0.81 | TRPV1 (0.62) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL23721294 | 0.80 | POLB (0.59) | NPC1HTTRAB9ALMNACYP1A2 | |
| SCHEMBL6531158 | 0.80 | TRPV1 (0.64) | NPC1HTTRAB9ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12403139-B2 | Methods and compositions for prevention and treatment of cardiac hypertrophy | UNIVERSITY OF HAWAII (US) | 2025-09-02 | — | — | US | disclosed |
| US-20240189303-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIVERSITY OF HAWAII | 2024-06-13 | — | — | US | disclosed |