Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 16/20 | 0.55 |
| ▸ | DRD2 | P14416 | 15/20 | 0.55 |
| ▸ | DRD4 | P21917 | 6/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14270569 | 0.77 | DRD2 (0.72) | DRD3DRD2DRD4ADRA1A | |
| SCHEMBL30964289 | 0.74 | DRD2 (0.55) | DRD3DRD2 | |
| SCHEMBL1193545 | 0.72 | DRD2 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL14270571 | 0.72 | DRD2 (0.66) | DRD3DRD2DRD4 | |
| SCHEMBL14494936 | 0.71 | DRD2 (0.74) | DRD3DRD2DRD4 | |
| SCHEMBL30964239 | 0.70 | DRD2 (0.56) | DRD3DRD2 | |
| SCHEMBL1193607 | 0.70 | DRD2 (0.83) | DRD3DRD2DRD4ADRA1A | |
| SCHEMBL1896873 | 0.70 | DRD2 (0.72) | DRD3DRD2DRD4 | |
| SCHEMBL2782258 | 0.70 | DRD2 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL12164841 | 0.70 | DRD2 (0.72) | DRD3DRD2DRD4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |