Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292590 | 1.00 | MEN1 (0.53) | MEN1KMT2AMAPTLMNACYP19A1 | |
| SCHEMBL14864858 | 0.87 | MAPT (0.58) | MEN1KMT2AMAPTLMNACYP19A1 | |
| SCHEMBL30965500 | 0.86 | HSPB1 (0.66) | MEN1KMT2AMAPTLMNACYP19A1 | |
| SCHEMBL23292646 | 0.86 | HSPB1 (0.66) | MEN1KMT2AMAPTLMNACYP19A1 | |
| SCHEMBL23292617 | 0.85 | MAPT (0.53) | MEN1KMT2AMAPTLMNACYP19A1 | |
| SCHEMBL23292631 | 0.83 | MEN1 (0.46) | MEN1KMT2AMAPTTBXA2RCRHBP | |
| SCHEMBL30965497 | 0.83 | MEN1 (0.46) | MEN1KMT2AMAPTTBXA2RCRHBP | |
| SCHEMBL23041348 | 0.83 | KMT2A (0.54) | MEN1KMT2AMAPTLMNACYP19A1 | |
| SCHEMBL7112512 | 0.83 | PTGS1 (0.47) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL29625925 | 0.83 | KMT2A (0.54) | MEN1KMT2AMAPTLMNACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513032-B | 4-Substituted phenyl-1, 3, 5-triazine derivatives as modulators of TRK receptors | 阿泽克制药公司 | 2024-07-02 | — | — | CN | disclosed |