Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25031328 | 0.90 | CRBN (0.38) | CRBNDDB1OPRM1OPRK1OPRL1 | |
| SCHEMBL30475498 | 0.90 | CRBN (0.38) | CRBNDDB1OPRM1OPRK1OPRL1 | |
| SCHEMBL25029416 | 0.89 | CRBN (0.38) | CRBNDDB1OPRM1OPRK1OPRL1 | |
| SCHEMBL25035179 | 0.87 | CRBN (0.35) | CRBNDDB1IKZF3POLB | |
| SCHEMBL30981492 | 0.87 | CRBN (0.40) | CRBNDDB1POLB | |
| SCHEMBL27224949 | 0.86 | CRBN (0.41) | CRBNDDB1IKZF2IKZF3 | |
| SCHEMBL25031339 | 0.86 | CRBN (0.36) | CRBNDDB1IKZF3POLB | |
| SCHEMBL30479046 | 0.86 | CRBN (0.36) | CRBNDDB1IKZF3POLB | |
| SCHEMBL25035207 | 0.86 | CRBN (0.37) | CRBNDDB1IKZF3POLB | |
| SCHEMBL30475495 | 0.86 | CRBN (0.37) | CRBNDDB1IKZF3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |