Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034669 | 1.00 | SLC9A1 (0.56) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL1675731 | 0.91 | SLC9A1 (0.63) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL30467198 | 0.91 | SLC9A1 (0.63) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL284672 | 0.88 | SLC9A1 (0.66) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL4154129 | 0.82 | SLC9A1 (0.59) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL31483490 | 0.81 | SLC9A1 (0.63) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL17966325 | 0.80 | EGLN3 (0.59) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL31483489 | 0.80 | SLC9A1 (0.61) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL8511223 | 0.79 | SLC9A1 (0.63) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL2272614 | 0.79 | SLC9A1 (0.46) | SLC9A1GRM2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |