Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965700 | 0.91 | CRBN (0.50) | CRBNDDB1SMN1; SMN2NPC1MAPT | |
| SCHEMBL30965829 | 0.86 | DDB1 (0.50) | CRBNDDB1HDAC8 | |
| SCHEMBL30376308 | 0.81 | CRBN (0.57) | CRBNDDB1SMN1; SMN2NPC1MAPT | |
| SCHEMBL25845885 | 0.81 | CRBN (0.57) | CRBNDDB1SMN1; SMN2NPC1MAPT | |
| SCHEMBL30965661 | 0.80 | DDB1 (0.61) | CRBNDDB1 | |
| SCHEMBL30965668 | 0.80 | DDB1 (0.50) | CRBNDDB1HDAC8 | |
| SCHEMBL30965572 | 0.80 | CRBN (0.48) | CRBNDDB1SMN1; SMN2NPC1MAPT | |
| SCHEMBL30965527 | 0.78 | MAPT (0.50) | SMN1; SMN2NPC1MAPTRAB9ATP53 | |
| SCHEMBL30965582 | 0.78 | DDB1 (0.52) | CRBNDDB1HDAC8 | |
| SCHEMBL31447908 | 0.76 | DDB1 (0.65) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |