Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965668 | 0.93 | DDB1 (0.50) | DDB1CRBNHDAC8DRD2 | |
| SCHEMBL30965582 | 0.90 | DDB1 (0.52) | DDB1CRBNHDAC8DRD2 | |
| SCHEMBL30981020 | 0.87 | DRD2 (0.54) | DDB1CRBNDRD2 | |
| SCHEMBL30965612 | 0.86 | CRBN (0.48) | DDB1CRBNHDAC8 | |
| SCHEMBL25024152 | 0.86 | CRBN (0.47) | DDB1CRBNHDAC8DRD2 | |
| SCHEMBL30981069 | 0.85 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL25169537 | 0.84 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL30919893 | 0.84 | CRBN (0.52) | DDB1CRBNHDAC8 | |
| SCHEMBL30981074 | 0.84 | DRD2 (0.51) | DDB1CRBNDRD2 | |
| SCHEMBL29199173 | 0.83 | DDB1 (0.64) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |