Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.43 |
| ▸ | DRD2 | P14416 | 10/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965552 | 0.94 | CRBN (0.43) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL30965536 | 0.93 | DDB1 (0.41) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL30965609 | 0.92 | CRBN (0.41) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL30965781 | 0.89 | CRBN (0.39) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL30965638 | 0.87 | ESR1 (0.40) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL25024306 | 0.87 | CRBN (0.47) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL30981368 | 0.87 | CRBN (0.47) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL30981152 | 0.87 | CRBN (0.47) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL30965521 | 0.86 | CRBN (0.47) | CRBNDDB1DRD2DRD3ESR1 | |
| SCHEMBL30965618 | 0.86 | CRBN (0.45) | CRBNDDB1DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |