Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 9/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965703 | 0.94 | CRBN (0.42) | CRBNDDB1DRD2DRD3KCNA3 | |
| SCHEMBL27225107 | 0.91 | DRD2 (0.48) | CRBNDDB1DRD2DRD3HTR1A | |
| SCHEMBL30965558 | 0.91 | DRD2 (0.45) | CRBNDDB1DRD2DRD3KCNA3 | |
| SCHEMBL30965757 | 0.89 | CRBN (0.44) | CRBNDDB1DRD2DRD3DRD4 | |
| SCHEMBL30965799 | 0.87 | DRD2 (0.44) | CRBNDDB1DRD2DRD3KCNA3 | |
| SCHEMBL30915142 | 0.86 | CRBN (0.49) | CRBNDDB1DRD2DRD3KCNA3 | |
| SCHEMBL30965677 | 0.86 | CRBN (0.43) | CRBNDDB1DRD2DRD3HTR1A | |
| SCHEMBL30965827 | 0.85 | DDB1 (0.43) | CRBNDDB1DRD2DRD3KCNA3 | |
| SCHEMBL30965564 | 0.84 | CRBN (0.48) | CRBNDDB1DRD2DRD3DRD4 | |
| SCHEMBL30965523 | 0.84 | CRBN (0.46) | CRBNDDB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |