Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965585 | 0.91 | DDB1 (0.45) | CRBNDDB1DRD2SLC6A4 | |
| SCHEMBL30965649 | 0.86 | CRBN (0.47) | CRBNDDB1DRD2HTR1AADRA1D | |
| SCHEMBL30981317 | 0.85 | DDB1 (0.47) | CRBNDDB1DRD2 | |
| SCHEMBL30981244 | 0.85 | DDB1 (0.47) | CRBNDDB1DRD2 | |
| SCHEMBL30965531 | 0.85 | DDB1 (0.47) | CRBNDDB1DRD2 | |
| SCHEMBL30981256 | 0.85 | DDB1 (0.66) | CRBNDDB1 | |
| SCHEMBL31487398 | 0.84 | DDB1 (0.55) | CRBNDDB1DRD2 | |
| SCHEMBL30915166 | 0.83 | CRBN (0.51) | CRBNDDB1 | |
| SCHEMBL30981557 | 0.81 | CRBN (0.67) | CRBNDDB1 | |
| SCHEMBL30981480 | 0.81 | CRBN (0.67) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |