SCHEMBL31487398

SCHEMBL31487398

O=C1CCC(Nc2ccc(N3CCN(CCC4CCNCC4)CC3)cc2F)C(=O)N1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 19/20 0.55
CRBN Q96SW2 19/20 0.55
DRD2 P14416 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30981244 0.90 DDB1 (0.47) DDB1CRBNDRD2DRD3
SCHEMBL30965531 0.90 DDB1 (0.47) DDB1CRBNDRD2DRD3
SCHEMBL30981317 0.90 DDB1 (0.47) DDB1CRBNDRD2DRD3
SCHEMBL30965791 0.87 CRBN (0.47) DDB1CRBN
SCHEMBL30965585 0.86 DDB1 (0.45) DDB1CRBNDRD2
SCHEMBL30981557 0.85 CRBN (0.67) DDB1CRBN
SCHEMBL30981480 0.85 CRBN (0.67) DDB1CRBN
SCHEMBL30965704 0.85 CRBN (0.67) DDB1CRBN
Hydrochloric Acid SCHEMBL27178698 0.84 CRBN (0.66) DDB1CRBN
SCHEMBL30965744 0.84 CRBN (0.47) DDB1CRBNDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119790057-A Novel PLK1 degradation inducing compounds 厄普特拉株式会社 2025-04-08 CN disclosed