Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487410 | 1.00 | GPR119 (0.46) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30981377 | 0.88 | GPR119 (0.45) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL26642195 | 0.87 | TLR9 (0.46) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL27225040 | 0.87 | GPR119 (0.44) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL24671637 | 0.85 | GPR119 (0.59) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL31714577 | 0.85 | GPR119 (0.46) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30801284 | 0.85 | GPR119 (0.59) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30965616 | 0.85 | TLR9 (0.50) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL31623047 | 0.85 | GPR119 (0.43) | GPR119CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL31583874 | 0.85 | GPR119 (0.48) | GPR119CCNT1CCNA2CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |