Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.76 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.76 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487404 | 1.00 | DDB1 (0.76) | DDB1CRBNWNT3AMAPTMEN1 | |
| SCHEMBL30965772 | 1.00 | DDB1 (0.76) | DDB1CRBNWNT3AMAPTMEN1 | |
| SCHEMBL23783277 | 0.94 | DDB1 (0.74) | DDB1CRBNGPR119 | |
| SCHEMBL31329764 | 0.94 | DDB1 (0.74) | DDB1CRBNGPR119 | |
| SCHEMBL30720114 | 0.88 | CRBN (0.63) | DDB1CRBNWNT3AMAPTMEN1 | |
| SCHEMBL27238864 | 0.88 | CRBN (0.63) | DDB1CRBNWNT3AMAPTMEN1 | |
| SCHEMBL27260521 | 0.88 | CRBN (0.63) | DDB1CRBNWNT3AMAPTMEN1 | |
| SCHEMBL20595405 | 0.87 | DDB1 (0.74) | DDB1CRBNMAPTMEN1TSHR | |
| SCHEMBL20595430 | 0.87 | DDB1 (0.74) | DDB1CRBNMAPTMEN1TSHR | |
| SCHEMBL30120110 | 0.87 | DDB1 (0.74) | DDB1CRBNMAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |