Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130066 | 0.90 | MAPT (0.54) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL29795685 | 0.90 | MAPT (0.54) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL6128555 | 0.88 | SMARCA2 (0.51) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL8221137 | 0.86 | SMARCA2 (0.55) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL30965579 | 0.86 | MAPT (0.53) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL31341901 | 0.86 | MAPT (0.46) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL21999659 | 0.86 | MAPT (0.53) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL31341985 | 0.85 | LMNA (0.44) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL25225007 | 0.84 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL21937028 | 0.84 | MAPT (0.51) | SMARCA2SMARCA4PBRM1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |