Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25305107 | 0.86 | ESR2 (0.44) | ESR2NR1H2USP30USP2SMN1; SMN2 | |
| SCHEMBL8252594 | 0.84 | ADORA1 (0.42) | ESR2NR1H2USP30USP2SMN1; SMN2 | |
| SCHEMBL11981955 | 0.83 | NR1H2 (0.41) | ESR2NR1H2USP30USP2SMN1; SMN2 | |
| SCHEMBL26134367 | 0.80 | USP30 (0.39) | USP30USP2SMN1; SMN2 | |
| SCHEMBL1081654 | 0.79 | ADORA1 (0.47) | ESR2NR1H2USP30USP2SMN1; SMN2 | |
| SCHEMBL2483591 | 0.77 | ADORA1 (0.47) | ESR2NR1H2USP30USP2SMN1; SMN2 | |
| SCHEMBL2809259 | 0.76 | ESR2 (0.51) | ESR2NR1H2USP30MAPTMAPK1 | |
| SCHEMBL38653270 | 0.76 | ESR2 (0.41) | ESR2NR1H2USP30ADORA1MAPT | |
| SCHEMBL25934807 | 0.76 | ESR2 (0.46) | ESR2NR1H2USP30ADORA1MAPT | |
| SCHEMBL29023102 | 0.75 | USP30 (0.37) | ESR2NR1H2USP30USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024120378-A2 | TRIAZOLE COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-13 | — | — | WO | disclosed |