Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965884 | 0.80 | ESR2 (0.41) | USP30USP2SMN1; SMN2 | |
| SCHEMBL16051476 | 0.80 | USP30 (0.40) | USP30HDAC2HDAC1USP2SMN1; SMN2 | |
| SCHEMBL23584405 | 0.77 | USP30 (0.40) | USP30HDAC2HDAC1USP2SMN1; SMN2 | |
| SCHEMBL14297530 | 0.75 | USP2 (0.45) | USP2SMN1; SMN2GPR119SCD5CYP11B2 | |
| SCHEMBL26134743 | 0.75 | SCD5 (0.42) | USP30HDAC2HDAC1GPR119SCD5 | |
| SCHEMBL19693266 | 0.73 | SCD5 (0.42) | USP30HDAC2HDAC1USP2SMN1; SMN2 | |
| SCHEMBL20396083 | 0.73 | USP30 (0.42) | USP30USP2SMN1; SMN2GPR119 | |
| SCHEMBL30775976 | 0.72 | USP2 (0.40) | USP30HDAC2HDAC1USP2SMN1; SMN2 | |
| SCHEMBL26108122 | 0.72 | GPR119 (0.39) | HDAC2HDAC1USP2SMN1; SMN2GPR119 | |
| SCHEMBL25305107 | 0.72 | ESR2 (0.44) | USP30USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2024091370-A1 | 5,6-FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |