Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.39 |
| ▸ | RORC | P51449 | 7/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785903 | 0.82 | TSHR (0.39) | GSK3ARORCMAPTGSK3BNR1I3 | |
| SCHEMBL30785915 | 0.80 | GSK3A (0.41) | GSK3ARORCMAPTGSK3BTSHR | |
| SCHEMBL29195527 | 0.75 | TSHR (0.40) | GSK3ARORCMAPTGSK3BTSHR | |
| SCHEMBL30778525 | 0.74 | TSHR (0.39) | GSK3ARORCMAPTCA12CA1 | |
| SCHEMBL31239543 | 0.73 | TSHR (0.38) | RORCCA12CA1CA9TSHR | |
| SCHEMBL31239522 | 0.73 | TSHR (0.38) | RORCCA12CA1CA9TSHR | |
| SCHEMBL30977495 | 0.72 | CYP17A1 (0.50) | RORCCA12CA1CA9CYP17A1 | |
| SCHEMBL30856684 | 0.71 | GSK3A (0.36) | GSK3AMETAXLMAPTGSK3B | |
| SCHEMBL30856653 | 0.71 | FFAR2 (0.38) | GSK3AMETAXLMAPTGSK3B | |
| SCHEMBL31373494 | 0.71 | TSHR (0.38) | TSHRFSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024083208-A1 | KIF18A PROTEIN INHIBITOR | 杭州邦顺制药有限公司 | 2024-04-25 | — | — | WO | disclosed |