Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | ILK | Q13418 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050082 | 1.00 | AHR (0.60) | AHRILKAPPMAPTTP53 | |
| SCHEMBL30365100 | 1.00 | AHR (0.60) | AHRILKAPPMAPTTP53 | |
| Aminomethylamide SCHEMBL5692113 | 0.89 | AHR (0.53) | AHRILKAPPMAPTTP53 | |
| SCHEMBL5691118 | 0.89 | APP (0.68) | ILKAPPMAPTKDM4ENPC1 | |
| SCHEMBL20161415 | 0.89 | AHR (0.60) | AHRILKAPPMAPTTP53 | |
| Aminomethylamide SCHEMBL5692730 | 0.89 | AHR (0.52) | AHRILKAPPMAPTTP53 | |
| Alanine SCHEMBL5691734 | 0.89 | AHR (0.49) | AHRILKAPPMAPTTP53 | |
| SCHEMBL5692717 | 0.89 | AHR (0.52) | AHRILKAPPMAPTTP53 | |
| Hydrochloric Acid SCHEMBL5691360 | 0.88 | AHR (0.51) | AHRILKAPPMAPTTP53 | |
| SCHEMBL30966535 | 0.86 | AHR (0.56) | AHRILKAPPMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111166744-B | Use of 4- (benzothiazol-2-yl) arylamine compound for treating gastric cancer | 诺丁汉大学 | 2024-06-25 | — | — | CN | claimed |
| CN-111166744-B | Use of 4- (benzothiazol-2-yl) arylamine compound for treating gastric cancer | 诺丁汉大学 | 2024-06-25 | — | — | CN | disclosed |