Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.47 |
| ▸ | RELA | Q04206 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | ILK | Q13418 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminomethylamide SCHEMBL5692730 | 0.99 | AHR (0.52) | AHRNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL30966554 | 0.89 | AHR (0.60) | AHRNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL30365100 | 0.89 | AHR (0.60) | AHRNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL3050082 | 0.89 | AHR (0.60) | AHRNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL5692717 | 0.88 | AHR (0.52) | AHRNPC1NFKB1RAB9ANFKB2 | |
| Hydrochloric Acid SCHEMBL5691360 | 0.87 | AHR (0.51) | AHRNPC1NFKB1RAB9ANFKB2 | |
| Alanine SCHEMBL5691734 | 0.86 | AHR (0.49) | AHRNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL5692785 | 0.84 | AHR (0.44) | AHRNPC1NFKB1RAB9ANFKB2 | |
| Hydrochloric Acid SCHEMBL5691320 | 0.84 | AHR (0.44) | AHRNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL5691118 | 0.80 | APP (0.68) | NPC1RAB9AILKAPPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204650-B1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | CANCER RES VENTURES LTD (GB) | 2006-04-19 | — | — | EP | claimed |