Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.41 |
| ▸ | MICA | Q29983 | 2/20 | 0.41 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283696 | 1.00 | ITGA5 (0.44) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL21821297 | 0.88 | TACR1 (0.48) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL19283810 | 0.87 | KLRK1 (0.53) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL21821288 | 0.86 | KLRK1 (0.52) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL19283862 | 0.86 | KLRK1 (0.52) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL19283725 | 0.85 | ITGA5 (0.48) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL21821319 | 0.85 | ITGA5 (0.49) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL19283627 | 0.84 | ITGA5 (0.46) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL21821304 | 0.84 | HRH4 (0.49) | ITGA5ITGB6ITGB8MTORKLRK1 | |
| SCHEMBL21821293 | 0.83 | ITGA5 (0.46) | ITGA5ITGB6ITGB8MTORKLRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618979-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics Inc. (US) | 2025-09-24 | — | — | EP | claimed |
| WO-2024108155-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | claimed |
| EP-4618979-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108155-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |